Reading Assignment #20

予習の仕方

1. nature NEWS

注:この記事は2023年 4月9日現在はオープンアクセスですが、今後限定公開となった場合は、学内からのみアクセスするか、学外から読む場合は、VPN接続してください。

Article Title

https://www.nature.com/articles/d41586-020-01658-1

2. Quiz

Answer the following questions.

Exercise: Answer the following questions.


1. Which of the following is the word "workings" in "the workings of proteins that cannot easily be examined" in meaning to?

a) labor

b) execution

c) mechanism


2. Which of the following is the achievement recently made with the technique of cryogenic-electron microscopy? 

a) Mapping the 3D shapes of proteins for the first time in the history of microscopy.  

b) Perceiving individual atoms in a protein for the first time in the history of microscopy. 

c) Understanding the workings of proteins contained in healthy and unhealthy tissue.


3. Which best describes the word "breakthrough" used in "The breakthrough, reported by two laboratories late last month"?

a) A sudden or significant advance that removes a barrier.

b) A forward movement.

c) An instance of improvement in importance.


4. How long has the technique of cryogenic-electron microscopy been around?

a) It's only been used in the last 10 years. 

b) It's been around for decades. 

c) It has only been available in the last several years.


5. Which of the following best explains the order of actions taken in cryogenic-electron microscopy?

a) flash-freeze samples - record ricocheting electrons - fire electrons at them - analyze images

b) flash-freeze samples - fire electrons at them - analyze images - record ricocheting electrons

c) flash-freeze samples - fire electrons at them - record ricocheting electrons - analyze images


6. Which of the following statements is correct about X-ray crystallography?

a) It uses diffraction patterns to obtain atomic-resolution structures. 

b) It requires a sample in a purified solution in order for it to be studied. 

c) It studies samples by firing electrons at them. 


7. Which of the following is the word "largely" in "scientists have had to largely rely on" closest in meaning to?

a) fully

b) wholly

c) mainly


8. Which of the following best defines the word "stable" in "as stable as apoferritin"

a) not likely to move

b) not liable to change

c) not easy to upset


9. What will probably happen to X-ray crystallography?

a) It will go out of use soon. 

b) It will be used as much as cryogenic-electron microscopy for many years to come.

c) It will continue to be used but probably less often.   


10. Which of the following is the word "retain" in "crystallography will retain some appeal" closest in meaning to?

a) stay in contact with

b) continue to have

c) keep track of